Renal failure,hemodialysis
Conditions
Interventions
Low-Risk Group (LPEW):None
High-Risk Group (HPEW):None
Sponsors
Shanghai East Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Regular hemodialysis for more than 3 months; 2. Age between 18 and 80 years; 3. If complicated with cardiovascular disease, able to receive standard antiplatelet therapy, ACEI/ARB, CCB, etc.; 4. Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Acute cardiovascular or cerebrovascular events within 3 months prior to screening; 2. Active infection; 3. Active liver disease or abnormal liver function (ALT or AST > 2.5 times the upper limit of normal) or history of liver cirrhosis; 4. History of cardiac surgery within 3 months prior to screening; 5. Diagnosis of malignancy or ongoing radiotherapy/chemotherapy within 3 months prior to screening; 6. Life-threatening severe infection within 3 months prior to screening; 7. Pregnant or lactating women, or patients on estrogen replacement therapy; 8. Active infectious diseases such as active tuberculosis, HIV infection, etc.; 9. Patients with psychiatric disorders taking psychotropic medications; 10. Patients assessed by the physician as difficult to follow up or with poor compliance, unsuitable for enrollment; 11. Patients unwilling to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MACE;Cardiovascular Disease-Related Death; | — |
Secondary
| Measure | Time frame |
|---|---|
| All-Cause Mortality;PEW score;Echocardiographic parameters;Quality of Life Score;Hospitalization;Complete blood count (CBC),Kidney function parameters,Liver function tests (LFTs),Serum lipid parameters,Cardiac failure biomarkers,Inflammatory biomarkers,Dialysis adequacy indices; | — |
Countries
China
Contacts
Public ContactLiu Na
Shanghai East Hospital
Outcome results
None listed