congenital heart disease, CHD
Conditions
Interventions
Toddler group (1 to 3 years):Esketamine is administered intranasally for preoperative sedation
Infant group (6 months to 1 year):Esketamine is administered intranasally for preoperative sedation
toddler group (1 to 3 years):Esketamine is administered intranasally for preoperative sedation
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
0.5 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1.Children with left-to-right shunt congenital heart disease who undergo elective surgery under general anesthesia, male or female; 2.ASA II-III; 3.Age is 6 months ~ 6 years old;
Exclusion criteria
Exclusion criteria: 1.The child's guardian refuses to participate; 2.Allergy to esketamine; 3.The child has abnormal nasal anatomy or intranasal bleeding; 4.The child had abnormal liver and kidney function; 5.The child has abnormal cardiac function; 6.Use of other sedative medications before surgery;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Calming effect;Calming effect; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate;Respiratory rate;Oxygen saturation;Non-invasive blood pressure; | — |
Countries
China
Contacts
Public ContactLifei Liu
Children's Hospital of Chongqing Medical University
Outcome results
None listed