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The impact of vagus nerve block on postoperative recovery quality in patients undergoing thoracoscopic lung surgery: a randomized, blinded, sham-block controlled trial

The impact of vagus nerve block on postoperative recovery quality in patients undergoing thoracoscopic lung surgery: a randomized, blinded, sham-block controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127580
Enrollment
Unknown
Registered
2026-07-02
Start date
2026-07-02
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer that can be treated with feasible single-port or multi-port video-assisted thoracoscopic surgery (VATS) for lobectomy or segmentectomy

Interventions

Control group (non-vagus nerve block group:After the surgery begins, under VATS assistance, the surgeon visually performs the action of blocking the vagus nerve as if administering medication, without
Experimental group (vagus nerve block group):After the operation began, intrathoracic vagus nerve block was performed directly under the assistance of VATS during the operation. Identify the odd venou

Sponsors

Peking University First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age: 18–75 years; ASA classification: I–III; 2.To undergo single-orifice-port thoracoscopic lobectomy or segmentectomy; 3.Preoperative pulmonary function test showing FEV1 >= 60% of predicted value; 4.Body mass index (BMI): 18–30 kg/m²; 5.Sign the informed consent form;

Exclusion criteria

Exclusion criteria: 1.History of thoracic surgery or thoracic radiotherapy; 2.ASA classification IV or higher; 3.Coagulation disorders (INR> 1.5, platelet count <100 × 10?/L); 4.History of local anesthesia drug allergy; 5.History of chronic pain or long-term use of opioids; 6.Cognitive dysfunction preventing completion of the QoR-15 assessment;

Design outcomes

Primary

MeasureTime frame
QoR-15 score at 24 hours postoperatively;

Secondary

MeasureTime frame
The severity of pain in post-operative patients;The number of times rescue analgesia is required post-operatively;Post-operative nausea and vomiting (PONV);Time of first post-operative mobilisation;Quality of sleep on the day of surgery (Campbell Scale);Length of hospital stay following surgery;Incidence of complications during hospitalisation;Safety indicators: including hoarseness, respiration-related adverse events, and bradycardia;

Countries

China

Contacts

Public ContactLin Gang

Peking University First Hospital

lingang0608@163.com+86 10 83572417

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026