Depressive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The age should be >=12 years old and 17 points, Yang's manic scale <4 points; 4. Take escithalan or sertraline as an antidepressant; 5. Participate voluntarily and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Combined with other mental disorders (bipolar disorder, schizophrenia, etc.); 2. Suffering from intellectual disability; 3. There is a history of substance abuse or dependence within 6 months before the assessment; 4. Combined with serious somatic diseases or organic diseases in the brain (traumatic brain injury, cerebral infarction, cerebral hemorrhage, etc.); 5. Other situations that are not suitable for this project (such as women who are pregnant, lactating or planned to become pregnant, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Hamilton Depression Rating Scale 17-item (HAMD-17) score from baseline to week 4 after the start of intervention;Change in HAMD-17 score;Change in MEQ-5 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in PSQI score;The marked efficacy from baseline to the 2nd and 4th weeks after the intervention began (marked efficacy was defined as a decrease of > =50% in the total score of HAMD-17 at the end of the 2nd week co;Change in HAMA score;Changes in the score of the Baker Depression Table-II (BDI-II); | — |
Countries
China
Contacts
Southern Medical University Southern Hospital