Pelvic floor disorders
Conditions
Interventions
Healthy control group:None
Sponsors
Fuzhou University Affiliated Provincial Hospital
Eligibility
Sex/Gender
Female
Age
25 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.GDM group: Diagnostic criteria: (1) Meeting the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria (fasting plasma glucose >= 5.1 mmol/L, 1-hour OGTT >= 10.0 mmol/L, 2-hour OGTT >= 8.5 mmol/L); (2) Baseline characteristics: singleton pregnancy, vaginal delivery, aged 25-40 years, BMI 18.5-30 kg/m², HbA1c >= 5.7%; (3) Source: Provincial Hospital Affiliated to Fuzhou University. 2.Healthy control group: (1) Matching criteria: age ± 2 years, BMI ±1 kg/m², gestational age ±1 week; (2) Metabolic indicators: HbA1c < 5.6%, no history of glucose metabolism disorders; (3) Mode of delivery: singleton vaginal delivery, neonatal birth weight 2500–4000g.
Exclusion criteria
Exclusion criteria: 1.History of pelvic floor surgery or severe pelvic organ prolapse (POP-Q stage III-IV); 2.Complicated with other metabolic diseases (e.g., hyperthyroidism, Cushing's syndrome); 3.Severe pregnancy complications (e.g., gestational hypertension, preeclampsia); 4.Contraindications to MRI/ultrasound examination (e.g., metal implants, allergic predisposition).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| severity of urinary incontinence ;biomechanical parameter of pelvic floor muscles ;morphological parameter ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Levator hiatus parameters (detailed pelvic configuration parameters (levator plate angle, pubic-urethral gap, and contraction and expansion rates of the levator hiatus), high-frequency ultrasound parameters (muscle bundle thickness, fiber orientation distribution, and echo percentage); | — |
Countries
China
Contacts
Public ContactYijia Luo
Fuzhou University Affiliated Provincial Hospital
Outcome results
None listed