Neuropathic Pain after Spinal Cord Injury
Conditions
Interventions
Control group:Transcutaneous vagus nerve electrical stimulation (sham stimulation)
Experimental group:transcutaneous auricular vagus nerve stimulation (active stimulation)
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Meet the diagnostic criteria for NP, with motor and sensory dysfunction in the spinal cord innervated areas below the level of injury, and patient-reported pain such as burning pain, allodynia, stabbing pain, etc; 2.Stable vital signs, clear consciousness, ability to express themselves clearly, and pain occurring after SCI; 3.No serious complications; 4.Patients have given informed consent and signed the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Individuals with mental illness or other serious comorbidities; 2.Those with severe cardiac, cerebral, or other internal medical conditions; 3.Individuals with contraindications such as having a cardiac pacemaker, cochlear implant, or any other metallic foreign bodies or implanted electronic devices, or those with other examination abnormalities that, in the investigator's judgment, render them unsuitable for participation in this trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short-Form McGill Pain Questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activities of Daily Living (ADL) scale score;Somatosensory Evoked Potentials;Leeds Assessment of Neuropathic Symptoms and Signs;Interleukin-6;Generalized Anxiety Disorder-7 Score;Douleur Neuropathique 4 questions;Motor Evoked Potentials (MEP);Functional Near-Infrared Spectroscopy (fNIRS);Patient Health Questionnaire-9 (PHQ-9);Chinese version of the World Health Organization Quality of Life Brief Scale (WHOQOL-BREF); | — |
Countries
China
Contacts
Public ContactYinxu Wang
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed