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Effects of Hyperbaric Oxygen Therapy on Clinical Phenotypes of Skin Photoaging: A Prospective Clinical Trial

Effects of Hyperbaric Oxygen Therapy on Clinical Phenotypes of Skin Photoaging: A Prospective Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127553
Enrollment
Unknown
Registered
2026-07-02
Start date
2026-07-09
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin photoaging

Interventions

Moderate skin photoaging group: 35–50 years old:hyperbaric oxygen therapy
Progressive skin photoaging group: 50–60 years old:hyperbaric oxygen therapy
Severe skin photoaging group: >= 60 years old.:hyperbaric oxygen therapy

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Aged 35 years or above, capable of self-care, with good functional and cognitive status. 2.No contraindications to hyperbaric oxygen therapy (HBOT), including untreated pneumothorax, active internal bleeding, concurrent use of certain antitumor drugs (such as cisplatin or doxorubicin), claustrophobia, etc. 3.Signed informed consent form.

Exclusion criteria

Exclusion criteria: 1.Individuals who have received HBOT for any reason within the past three months. 2.Individuals with a history of malignant tumor within the past one year. 3.Individuals with contraindications related to hyperbaric oxygen therapy, including untreated pneumothorax, active internal bleeding, concurrent use of certain antitumor drugs (such as cisplatin or doxorubicin), claustrophobia, etc. 4.Individuals with uncontrolled hypertension, i.e., systolic blood pressure = 160 mmHg and diastolic blood pressure = 100 mmHg. 5.Individuals with any pathological cognitive decline. 6.Individuals who have undergone facial photoelectric therapy or other treatments or surgeries that may affect the results within the past three months. 7.Smokers.

Design outcomes

Primary

MeasureTime frame
Improvement rate of skin photoaging characteristics;

Secondary

MeasureTime frame
Participant self-rated satisfaction (PAS);

Countries

China

Contacts

Public ContactYihon Zhou

Affiliated Hospital of Guangdong Medical University

zhouyihong@139.com+86 759 2387551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026