Preeclampsia
Conditions
Interventions
Single-Center Prospective Cohort Study – Normal Pregnancy Control Group without PE:None
Single-Center Prospective Cohort Study – Preeclampsia (PE) Group:None
Prospective Case-Control Study – 1:2 Matched Normal Pregnancy Control Group:None
Multicenter Retrospective Cohort Study – Normal Pregnancy Control Group without PE (Preeclampsia):None
Multicenter Retrospective Cohort Study – Preeclampsia Case Group:None
Prospective Case-Control Study – Preeclampsia (PE) Case Group:None
Sponsors
Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.Chinese nationality; 2.6–13?6 weeks of gestation; 3.All antenatal check-ups and delivery at the registered hospital; 4.Residing in the current location for at least 1 consecutive year; 5.Free from statutorily notifiable infectious diseases including hepatitis B, syphilis, and HIV/AIDS.
Exclusion criteria
Exclusion criteria: 1.Incomplete essential test results during early pregnancy; History of hypertension; Severe kidney disease, severe chronic liver disease, autoimmune diseases, etc.; Incomplete basic information such as demographic characteristics; Loss to follow-up. 2.Severe kidney disease, severe chronic liver disease, autoimmune diseases, or related disorders; History of hypertension; Missing basic information; Missing key laboratory indicators during early pregnancy; Termination of pregnancy due to social factors or major fetal malformations; Withdrawal from enrollment or loss to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preeclampsia (PE);Mean arterial pressure (MAP);Liver Stiffness Measurement (LSM);FIB-4 score;Pre-pregnancy BMI;Gestational hypertension;Hepatic Steatosis Index (HSI); | — |
Countries
China
Contacts
Public ContactZhang Lin
Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Outcome results
None listed