Rotator cuff injury
Conditions
Interventions
conventional-dose group:Liposomal bupivacaine 10 mL (133 mg) is diluted with 10 mL of normal saline to a total volume of 20 mL.
low-dose group:Liposomal bupivacaine 7.5 mL (100 mg) is diluted with 12.5 mL of normal saline to a total volume of 20 mL.
Sponsors
The FIrst Affiliated Hospital, College of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18–65 years, either sex; 2. American Society of Anesthesiologists (ASA) physical status I–III; 3. Scheduled to undergo elective shoulder arthroscopy; 4. Written informed consent provided by the patient or their legal guardian; 5. Willing to accept perioperative follow-up.
Exclusion criteria
Exclusion criteria: 1. Body mass index (BMI) = 34 kg/m²; 2. Severe coagulation disorders; 3. Severe heart disease (e.g., New York Heart Association [NYHA] functional class II or higher heart failure, aortic stenosis, or severe cardiac arrhythmias); 4. Known allergy to local anesthetics or study drugs; 5. Alcohol abuse or opioid dependence; 6. Massive rotator cuff tear (tear >5 cm, involving two or more tendon tears).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS AUC; | — |
Secondary
| Measure | Time frame |
|---|---|
| duration of motor blockade; | — |
Countries
China
Contacts
Public ContactXianhui Kang
The FIrst Affiliated Hospital, College of Medicine, Zhejiang University
Outcome results
None listed