Skip to content

Comparison of two respiratory support methods (high-flow oxygen vs. non-invasive ventilation) in adult patients after breathing tube removal following heart surgery

Comparison of clinical efficacy between high-flow nasal cannula oxygen therapy and non-invasive positive pressure ventilation in extubated adult patients after cardiac surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127492
Enrollment
Unknown
Registered
2026-07-01
Start date
2026-09-03
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart disease

Interventions

NIPPV group:None

Sponsors

WEST CHINA TIANFU HOSPITAL,SICHUAN UNIVERSITY
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients undergoing their first attempt at extubation after cardiac surgery with cardiopulmonary bypass; 2. Age >= 18 years; 3. Meeting any one of the following criteria for high risk of extubation failure: (1) Body mass index > 30 kg/m^2; (2) Age > 65 years; (3) Preoperative left ventricular ejection fraction (LVEF) = 4 hours.

Exclusion criteria

Exclusion criteria: 1.Patients who have never attempted extubation; 2.Tracheostomized patients without a prior extubation attempt; 3.Patients who refuse reintubation; 4.Patients whose initial treatment duration is < 4 hours due to intolerance, respiratory deterioration, or other reasons;

Design outcomes

Primary

MeasureTime frame
Length of ICU stay;

Secondary

MeasureTime frame
Length of hospital stay;72-hour reintubation rate;ICU mortality;In-hospital mortality;Changes in vital signs and oxygenation index (pre-extubation vs. 24 hours post-extubation);

Countries

China

Contacts

Public ContactJiao Lu

WEST CHINA TIANFU HOSPITAL,SICHUAN UNIVERSITY

1037507990@qq.com+86 28 8542 2369

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026