Chylothorax
Conditions
Interventions
Best dose exploration-A group:30 minutes before surgery, ICG injected into inguinal lymph nodes under ultrasound guidance at 0.2mg/kg
Best dose exploration-B group:30 minutes before surgery, ICG injected into inguinal lymph nodes under ultrasound guidance at 0.1mg/kg
Injection method comparison-A group (subcutaneous injection):30 minutes before surgery, optimal dose of ICG injected subcutaneously in the inguinal region
Injection method comparison-B group (lymph node injection):30 minutes before surgery, optimal dose of ICG injected into inguinal lymph nodes under ultrasound guidance
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for right thoracoscopic lung cancer surgery need to undergo mediastinal lymph node dissection; 2. The liver function was normal before the operation; 3. No history of indocyanine green or iodine allergy, and negative indocyanine green skin test; 4. Voluntarily participate in this study and sign the informed consent form for this study; 5. Age is over 18 years old and no more than 75 years old.
Exclusion criteria
Exclusion criteria: 1. Severe liver damage prior to the operation; 2. No diseases related to the lymphatic system; 3. Combine other uncontrolled co-morbidities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of thoracic duct imaging;Thoracic duct signal-to-background ratio (SBR); | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to fluorescence thoracic duct visualization;Duration of imaging;Thoracic duct signal-to-background ratio (SBR);Success rate of imaging;Procedure duration;Adverse events or complications; | — |
Countries
China
Contacts
Public ContactYang Feng
Peking University People's Hospital
Outcome results
None listed