Respiratory distress syndrome
Conditions
Interventions
CPAP group:Provide continuous positive airway pressure (CPAP)
Sequential therapy (HFNC–CPAP):Patients were initially treated with heated humidified high-flow nasal cannula (HFNC) oxygen therapy
if respiratory distress worsened, continuous pos
Sponsors
Chongqing Health Center for Women and Children
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: 1. Gestational age >= 35 weeks; 2. All neonates who developed respiratory distress or persistent cyanosis after the 1-minute resuscitation, requiring admission to the neonatal department, in accordance with the 2025 Neonatal Resuscitation Guidelines.
Exclusion criteria
Exclusion criteria: 1. Newborns with a heart rate < 100 beats per minute (bpm) between 1 minute after birth and NICU admission; 2. Parental refusal to provide informed consent; 3. Presence of congenital malformations affecting respiratory function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation rate within the first 3 days after birth; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of necrotizing enterocolitis (NEC, Bell stage >= II);Incidence of intraventricular hemorrhage (IVH, Papile grade >= III) after initiation of non?invasive ventilation;Incidence of air leaks during non?invasive ventilation;Length of hospital stay;Intubation rate within 7 days after birth;Nasal trauma; | — |
Countries
China
Contacts
Public ContactChen Long
Chongqing Health Center for Women and Children
Outcome results
None listed