Acute myeloid leukemia
Conditions
Interventions
Disease group:None
Healthy control group:None
Sponsors
Zhongshan People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18; 2. Gender: any; 3. Remaining peripheral blood from newly diagnosed AML patients or health check-up participants can be used for PBMC isolation; 4. Newly diagnosed AML patients have not received systemic treatment before sample collection; 5. Peripheral blood samples from health check-up participants are leftover samples, with no extra blood drawn; 6. Sample quality meets the requirements for in vitro experiments.
Exclusion criteria
Exclusion criteria: 1.Insufficient sample volume or PBMC quality failing to meet criteria; 2.Severely missing clinical data, making verification of eligibility impossible; 3.Samples deemed unsuitable for participation in this study by the investigator's judgment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytotoxic marker Granzyme B expression;Intracellular TNF-a expression;IFN-? expression; | — |
Secondary
| Measure | Time frame |
|---|---|
| T cell activation marker CD69 expression; | — |
Countries
China
Contacts
Public ContactYanping Feng
Zhongshan People's Hospital
Outcome results
None listed