Hemiplegia caused by ischemic stroke with lower limb dysfunction
Conditions
Interventions
Test group:Conventional early rehabilitation combined with supine knee flexion and extension training under blood flow restriction
Control group:Routine Early Rehabilitation and Supine Knee Flexion and Extension Training
Sponsors
Taizhou People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18–80 years, either sex; 2. Meet WHO diagnostic criteria for stroke, confirmed by cranial CT/MRI as ischemic stroke, with first-ever onset; 3. Onset within 7–14 days, vital signs stable, and no progression of neurological deficits; 4. Able to cooperate with rehabilitation training and assessment, without significant disturbance of consciousness; 5. Presence of unilateral lower extremity motor dysfunction, with Manual Muscle Testing (MMT) grade 1–3 on the affected side; 6. Mini-Mental State Examination (MMSE) score >=21, able to understand verbal instructions; 7. Written informed consent signed by the patient or legal representative.
Exclusion criteria
Exclusion criteria: 1. Hemorrhagic stroke; 2. History of lower extremity deep vein thrombosis (DVT) or positive screening findings; 3. Severe peripheral arterial disease, limb ischemia, Raynaud's disease, or local skin infection/breakdown; 4. Uncontrolled hypertension: SBP > 180 mmHg or DBP > 110 mmHg; 5. Severe cardiac insufficiency, respiratory failure, or malignant arrhythmias; 6. Lower extremity fracture, joint dislocation, severe osteoarthropathy, or joint contracture; 7. Pre-existing Parkinson's disease, spinal cord injury, Guillain-Barré syndrome, or other conditions affecting walking; 8. Coagulation abnormalities, bleeding tendency, or high risk for anticoagulation; 9. Inability to cooperate with training or assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cross-sectional area and thickness of quadriceps femoris; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activities of Daily Living;Thigh circumference;Quadriceps muscle strength;Deep vein thrombosis;The Manual Muscle Testing (MMT) standard grading method was adopted. The subject lies supine with the knee on the hemiplegic side fully extended. The examiner applies resistance and grades the quadric; | — |
Countries
China
Contacts
Public ContactJiangsu
Taizhou People's Hospital
Outcome results
None listed