Pulmonary nodules (possible early lung cancer), benign lung tumors, pulmonary bullae, spontaneous pneumothorax, which may be accompanied by chest tightness, chest pain, cough, or be asymptomatic
Conditions
Interventions
Alfentanil Group:Anesthesia induction was performed using alfentanil (15 µg/kg), and alfentanil (0.5-1.0 µg/kg/min) was continuously infused during the operation for maintenance, with precise titratio
Sufentanil Group:Anesthesia induction was performed using sufentanil (0.2 µg/kg), and sufentanil (0.15 µg/kg) was added as needed during the operation.
Sponsors
The First Affiliated Hospital of Gannan Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing thoracic day surgery; 2. 18 years <= age <= 70 years; 3. 18 kg/m^2 <= BMI <= 28 kg/m^2; 4. American Society of Anesthesiologists (ASA) physical status grade I-II; 5. No severe cardiopulmonary disease, hepatic or renal dysfunction, or other major diseases.
Exclusion criteria
Exclusion criteria: 1.Recent (within 2 weeks) respiratory tract infection; 2.Pregnant or breastfeeding women; 3.History of poorly controlled chronic respiratory diseases (e.g., asthma, chronic bronchitis, chronic obstructive pulmonary disease); 4.Known allergy or contraindication to the study drugs; 5.Cognitive or communication impairments that preclude completion of questionnaire assessments;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour resting pain Numerical Rating Scale score;24-hour Quality of Recovery-15 total score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of opioid-related adverse events;Incidence of chronic post-surgical pain at 3 months;Extubation time;Days alive and at home within 30 days postoperatively;48-hour QoR-15 total score;Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactYuan Liuqing
The First Affiliated Hospital of Gannan Medical University
Outcome results
None listed