Cervical HPV infection,Cervical intraepithelial neoplasia grade I (CIN I),Cervical intraepithelial neoplasia grade I (CIN I),Cervical intraepithelial neoplasia grade III (CIN III)
Conditions
Interventions
Novel HPV detection technology + cytology group:None
Current mature HPV detection technology + cytology group:None
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
Female
Age
21 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 21 and 64, with a complete uterus; 2. Good health condition and able to undergo routine cervical cancer screening; 3. Be willing to undergo colposcopy and biopsy; 4. Be able to understand the research procedures, voluntarily participate and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Women with suspected clinical pregnancy symptoms or within 8 weeks postpartum; 2. Those with a clear history of cervical cancer or precancerous lesions or pelvic radiotherapy; 3. Physically or mentally unable to undergo routine cervical cancer screening or unable to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Negative Percent Agreement (NPA);Total concordance rate;Positive agreement rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive Predictive Value (PPV);Sensitivity and specificity of CIN2+ detection;Sensitivity for detecting CIN2+;Positive Likelihood Ratio;Negative Likelihood Ratio;Negative Predictive Value (PPV); | — |
Countries
China
Contacts
Public ContactZhu Lan
Peking Union Medical College Hospital
Outcome results
None listed