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Development of cerebral perfusion monitoring system based on carotid hemodynamics and validation of postoperative cognitive function prediction ability

Development of cerebral perfusion monitoring system based on carotid hemodynamics and validation of postoperative cognitive function prediction ability

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127463
Enrollment
Unknown
Registered
2026-07-01
Start date
2026-07-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Cognitive Dysfunction

Interventions

B Group (Part II):None
A Group (Part I):None

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 65 years old; 2. ASA >= Class II; 3. Planned to undergo general anesthesia surgery; 4. Non-cardiac elective surgery patients; 5. Expected surgery time over 2 hours; 6. Voluntarily signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Emergency surgery; 2. Severe narrowing of both carotid arteries or other issues affecting ultrasound monitoring; 3. Surgeries that need neck exposure (like thyroid surgery, carotid surgery, or anterior neck surgery); 4. Changes in position during surgery (like needing to lie on your back, side, or stomach, or a combination); 5. Hearing or vision problems that make cognitive testing impossible; 6. Unexpected discharge or if someone refuses to take part in the study.

Design outcomes

Primary

MeasureTime frame
Carotid artery hemodynamic parameters;Regional Cerebral Oxygen Saturation;

Secondary

MeasureTime frame
Bispectral Index;

Countries

China

Contacts

Public ContactYang Zhou

Peking University Third Hospital

zhouyang@pku.edu.cn+86 10 82267272

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026