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Survival Outcomes of Different Surgical Approaches for Stage I Non-Small Cell Lung Cancer: Overall Survival and Disease-Free Survival Analysis

Intentional wedge resection demonstrates non-inferiority to segmentectomy or lobectomy in <=2 cm and CTR<=0.5 GGO-Dominant NSCLC: a retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127461
Enrollment
Unknown
Registered
2026-07-01
Start date
2026-04-24
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early-stage (Stage I) non-small cell lung cancer (NSCLC), specifically referring to Stage I NSCLC defined by the 9th edition of the TNM classification system

Interventions

Sponsors

Sichuan Science City Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.(1) Clinically diagnosed with stage I non-small cell lung cancer (NSCLC) in accordance with the 9th edition TNM staging system of the International Association for the Study of Lung Cancer (IASLC). (2) Preoperative thin-slice computed tomography (CT) confirmed peripheral lesions predominantly composed of ground-glass nodules, with a maximum diameter = 18 years, regardless of gender. 4. Follow-up duration >= 6 months, or until the occurrence of clinical outcome events such as death and disease recurrence. 5. Complete information on exposure factors and outcome indicators is available in the clinical data of patients. 6. Additional reasonable inclusion criteria may be supplemented on the premise that all the above criteria are satisfied.

Exclusion criteria

Exclusion criteria: 1.(1) Pathological diagnosis other than adenocarcinoma or squamous cell carcinoma; (2) Carcinoid tumors; (3) Evidence of lymph node metastasis or distant metastasis; (4) Receipt of neoadjuvant therapy; (5) Severe interstitial lung disease precluding the scheduled surgical procedure. 2. Incomplete medical records with missing critical information including exposure factors, outcome indicators and follow-up data; inability to contact patients, rendering data extraction and analysis unfeasible. 3. Loss to follow-up during the follow-up period. Definition of loss to follow-up: inability to contact patients, refusal of subsequent follow-up, or follow-up duration less than 6 months without any outcome events occurring. 4. Explicit refusal of study participation by patients or their families (with documented denial of research authorization in medical records). 5. Other conditions that may compromise the authenticity of study results, such as complicated mental disorders or cognitive impairment, leading to failure in follow-up compliance and data collection.

Design outcomes

Primary

MeasureTime frame
Disease-free survival;Overall survival;

Secondary

MeasureTime frame
Recurrence-free survival;Postoperative complications;Lung Cancer-Specific Survival;

Countries

China

Contacts

Public ContactYizong Feng

Sichuan Science City Hospital

619921074@qq.com+86 816 2493081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026