Chronic coronary syndrome
Conditions
Interventions
Normal CT-FFR Cohort:None
Abnormal CT-FFR Cohort:None
Sponsors
The second affiliated hospital of Zhejiang University school of medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years; 2.Clinical diagnosis of chronic coronary syndrome (CCS); 3.Completed coronary computed tomography angiography (CCTA) examination and successfully obtained CT-derived fractional flow reserve (CT-FFR) results; 4.The subject or their legal representative voluntarily participates in this study and has signed the written informed consent form;
Exclusion criteria
Exclusion criteria: 1.Acute coronary syndrome (ACS), including ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI), or acute episodes of unstable angina; 2.Unable to obtain valid CT-FFR results, or the image quality is insufficient to support analysis; 3.Pregnant patients or those who intend to become pregnant during the study period; 4.Non-cardiac comorbidities indicating a life expectancy of less than one year; 5.Failure to sign the informed consent form; 6.Inability to complete the follow-up or explicit refusal to participate in the follow-up; 7.Cognitive impairment or psychiatric disorders confirmed by clinical diagnosis or investigator assessment; 8.Patients who are illiterate or semi-literate, or who, due to any visual impairment or reading/writing disability, are unable to independently read the subject information sheet without assistance and are unable to personally provide written informed consent; 9.Any other conditions deemed unsuitable for participation in this study by the investigators;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite of All-cause Death, Myocardial Infarction (MI), or Ischemia-driven Revascularization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Subgroup Analysis of Imaging Features and Clinical Outcomes;Revascularization;Non-fatal Myocardial Infarction Including Periprocedural MI;Correlation of Non-invasive and Invasive Indices;CT Plaque Characteristics and Clinical Associations;All-cause Death and Cardiac Death;Target Vessel Failure;Health Economics Analysis;Non-Target Vessel or Non-Target Lesion Revascularization;Non-fatal Myocardial Infarction Excluding Periprocedural MI;Stroke;Primary Endpoint Excluding Periprocedural MI;Target Vessel or Target Lesion Revascularization;Composite of All-cause Death, Myocardial Infarction (MI), or Ischemia-driven Revascularization;Individual Components of the Primary Endpoint; | — |
Countries
China
Contacts
Public ContactJun Jiang
The second affiliated hospital of Zhejiang University school of medicine
Outcome results
None listed