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Correlation Analysis of C-reactive Protein, NT-proBNP, and PLR with the Efficacy of Triple Inhalation Therapy in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Correlation Analysis of C-reactive Protein, NT-proBNP, and PLR with the Efficacy of Triple Inhalation Therapy in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127451
Enrollment
Unknown
Registered
2026-07-01
Start date
2026-07-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

Observation Group:None

Sponsors

Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Met the relevant diagnostic criteria outlined in the Guidelines for the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease with Integrated Traditional Chinese and Western Medicine (2025 Edition). 2.All patients were in the acute phase. 3.Patients were able to tolerate and receive triple inhalation therapy. 4.Patients were mentally stable and fully conscious. 5.Both general demographic data and clinical examination records were complete.

Exclusion criteria

Exclusion criteria: 1. Patients with dysfunction of vital organs such as the kidneys, liver, or heart, or those with hematological diseases. 2. Patients who had undergone major surgery or received immunomodulators or glucocorticoids within the last 3 months. 3. Patients with other pulmonary diseases, such as asthma or pulmonary tuberculosis. 4. Patients with malignant wasting diseases. 5. Patients with immune system diseases. 6. Patients with cognitive impairment or psychiatric disorders. 7. Patients in the stable phase of the disease.

Design outcomes

Primary

MeasureTime frame
Pulmonary function;C-reactive protein (CRP); N-terminal pro b-type natriuretic peptide (NT-proBNP);

Secondary

MeasureTime frame
blood indicators;

Countries

China

Contacts

Public ContactHuang Chunhua

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

2521843262@qq.com+86 20 3407 1592

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026