Atrial fibrillation
Conditions
Interventions
Group A: First surgery, radiofrequency ablation:On the basis of conventional atrial fibrillation catheter ablation (posterior endocardial wall electrical isolation), additional dry pericardiocentesis
Group B: First operation, pulsed ablation:On the basis of conventional atrial fibrillation catheter ablation (posterior endocardial wall electrical isolation), additional dry pericardiocentesis and ep
Group C: Previous history of posterior wall isolation, reoperation:On the basis of conventional atrial fibrillation catheter ablation (posterior endocardial wall electrical isolation), additional dry
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18-80 years old, gender not limited. 2. Comply with the current indications of atrial fibrillation catheter ablation guidelines (symptomatic, drug-resistant). 3. Preoperative transesophageal ultrasound was used to rule out thrombus in the left atrium. 4. Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.There is a history of cardiac surgery or a possibility of severe pericardial adhesion in the past. 2. Severe valvular heart disease, severe left atrial enlargement (anteroposterior diameter > 55mm). 3. Severe coagulation dysfunction (INR>1.5, platelet count <50×10^9/L). 4. Acute coronary syndrome or cardiogenic shock. 5. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of transmural isolation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of epicardial electrical conduction in patients with prior posterior wall isolation;Incidence of acute electrical conduction recovery within 30 minutes;The difference in wall penetration success rates between radiofrequency ablation and pulse ablation;The consistency of endocardial and epicardial mapping results;The incidence of surgery-related adverse events; | — |
Countries
China
Contacts
Public ContactZhou Genqing
Shanghai General Hospital
Outcome results
None listed