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Pelvic Peritoneal Reconstruction to Prevent LARS After Low Rectal Resection: A Retrospective Analysis of Prospectively Enrolled Cohort

Pelvic Peritoneal Reconstruction to Prevent LARS After Low Rectal Resection: A Retrospective Analysis of Prospectively Enrolled Cohort

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127400
Enrollment
Unknown
Registered
2026-06-30
Start date
2026-06-30
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low rectal cancer (rectal adenocarcinoma)

Interventions

Reconstruction group (Pelvic peritoneal reconstruction during laparoscopic anterior resection for low rectal cancer):None
Control group (Laparoscopic Anterior Resection for Low Rectal Cancer):None

Sponsors

Wuxi people’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients who have been pathologically diagnosed with rectal adenocarcinoma, with the lower edge of the tumor =5 cm from the anus; 2. Successfully underwent laparoscopic low anterior resection for rectal cancer while preserving the anus; 3. Aged 18–75 years, with an ECOG score of 0–1; 4. No preoperative bowel dysfunction or history of anal incontinence; 5. Clinical and follow-up data are complete.

Exclusion criteria

Exclusion criteria: 1. Tumor has spread to distant areas or there are other malignant tumors; 2. Major organ dysfunction, unable to tolerate surgery; 3. History of previous pelvic surgery that might affect bowel function assessment; 4. Switching to non-sphincter-preserving surgery during operation; 5. Key data is missing, making statistical analysis impossible.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative small bowel pelvic descent;Overall incidence of low anterior resection syndrome (LARS) at 1 year postoperatively;

Secondary

MeasureTime frame
Intraoperative blood loss;Operative time;Overall incidence of perioperative complications;Postoperative intestinal function recovery indicators;Postoperative quality of life score;

Countries

China

Contacts

Public ContactTian Zhiqiang

Wuxi people’s Hospital

zhiqiangtiann@163.com+86 510 85350091

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026