stroke
Conditions
Interventions
Experimental group:All patients received comprehensive rehabilitation interventions including routine pharmacotherapy, physical agent therapy and exercise therapy in accordance with clinical guideline
Control group:All patients received comprehensive rehabilitation interventions consisting of routine pharmacotherapy, physical agent therapy and exercise therapy in line with clinical guidelines. Base
Sponsors
The First Affiliated Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18–80 years old; 2. Right-handed, confirmed by the Edinburgh Handedness Inventory; 3. First-ever unilateral stroke (ischemic or hemorrhagic) diagnosed via cranial CT or MRI, consistent with the diagnostic criteria specified in the 2024 Guidelines for the Prevention and Treatment of Cerebrovascular Diseases and 2023 Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke; 4. Disease course in the subacute phase (1 week to 6 months); 5. Impaired upper limb motor function, with a baseline Fugl-Meyer Assessment for Upper Extremity (FMA-UE) score <= 58 points (full score = 66 points); 6. Modified Ashworth Scale (MAS) grade <= 2 (indicating no or mild-to-moderate increased muscle tone); 7. Stable vital signs, clear consciousness, and ability to cooperate with all assessments and training instructions; 8. Voluntary participation with signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Previous history of stroke with residual upper limb motor dysfunction; 2. Severe limitation of upper limb joint range of motion, unhealed fractures, severe shoulder-hand syndrome, unrelieved shoulder subluxation, or other conditions that may interfere with robot-assisted training; 3. Personal or family history of epileptic seizures; 4. Electronic or metallic implants in the head or heart (e.g., intracranial aneurysm clips, brain pacemakers, cochlear implants, cardiac pacemakers, etc.); 5. Administration of central nervous system active drugs within the past week (e.g., benzodiazepines, baclofen, caffeine, theophylline, etc.); 6. Confirmed severe aphasia; Montreal Cognitive Assessment (MoCA) score <= 26 points (indicating cognitive dysfunction that impairs comprehension and cooperation during training); 7. Complicated with severe cardiac, pulmonary, hepatic or renal insufficiency, malignant tumors or other illnesses that prevent tolerance to rehabilitation training; 8. Received robot-assisted upper limb rehabilitation or other novel rehabilitation interventions within the past month, or botulinum toxin injection within 16 weeks prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer assessment for upper extremity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wolf motor function test;modified Barthel index;modified Ashworth scale; | — |
Countries
China
Contacts
Public ContactHua Yuan
The First Affiliated Hospital of Air Force Medical University
Outcome results
None listed