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A Study on the Survival of Oral Probiotics in the Human Gut

Study on the Colonization Efficiency of Probiotic Strain A in Human Gut

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127355
Enrollment
Unknown
Registered
2026-06-30
Start date
2026-07-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Experimental Group:Oral administration of Probiotic A

Sponsors

School of Life Sciences,East China Normal University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1.Healthy subjects aged 18-35 years old, regardless of gender, who voluntarily participate in this study and sign the informed consent form; 2.No infectious diseases and no definite acute or chronic diseases (such as gastrointestinal diseases, cardiovascular diseases, immune system diseases, etc.); 3.No known history of allergies (those who are allergic to probiotics, dairy products, experimental related reagents, etc. are excluded); 4.No intake of any probiotic products, antibiotics, or drugs affecting intestinal flora within 1 month prior to the start of the study; 5.Able to cooperate with the intervention, sample collection and related tests throughout the study period, with good compliance.

Exclusion criteria

Exclusion criteria: 1.Those whose age is not within the range of 18-35 years old, or who cannot provide valid identification; 2.Those with abnormal vital signs, infectious diseases, or acute/chronic diseases, especially gastrointestinal diseases, metabolic diseases, immunodeficiency, and other diseases that may affect intestinal flora; 3.Those with a history of allergies, or who may have an allergic risk to the Probiotic A product, test reagents, and other materials used in this study; 4.Those who have taken probiotics, antibiotics, intestinal regulators, or other drugs within 1 month prior to the start of the study, or have received intestinal-related treatment; 5.Those who are unable to cooperate with sample collection and testing, or have poor compliance, which may affect the research results; 6.Those with a history of intestinal surgery in the recent period.

Design outcomes

Primary

MeasureTime frame
Probiotic colonization quantity;

Countries

China

Contacts

Public ContactMeiling Zhang

School of Life Sciences,East China Normal University

mlzhang@bio.ecnu.edu.cn+86 21 54345354

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026