Internal and mixed hemorrhoids
Conditions
Interventions
Polidocanol group:None
Sponsors
Medical Center Hospital of Qionglai City
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years; 2.Diagnosis of internal or mixed hemorrhoids according to the Chinese Guidelines for the Diagnosis and Treatment of Hemorrhoids (2020); 3. Patients eligible for monotherapy or combination therapy with polidocanol as assessed by investigators; 4.Written informed consent and willingness to complete scheduled followup visits.
Exclusion criteria
Exclusion criteria: 1.Patients diagnosed with external hemorrhoids; 2.Patients allergic to polidocanol or any component of the polidocanol sclerosant; 3.Patients with severe systemic diseases (especially untreated); 4.Patients with acute inflammatory conditions in the anal area (anal infection, abscess) or with anal fissure; 5.Patients with fever; 6.Patients with bronchial asthma or known allergic predisposition; 7.Patients with severe vital organ disease or immunocompromised status; 8.Patients with chronic inflammatory bowel disease (e.g., Crohn's disease); 9.Patients with known hypercoagulable state; 10.Pregnant or lactating women, or those who are unwilling or unable to use contraception during the study; 11.Patients with a history of psychiatric disorders or neurological dysfunction; 12. Other conditions that the investigator deems unsuitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical response rate at week 12; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in pain VAS score;6-month recurrence rate;Patient satisfaction;Change in prolapse score;Change in itching VAS score;Change in HDSS and EQ-5D-3L scores;Change in bleeding score;Adverse event rate; | — |
Countries
China
Contacts
Public ContactLi Chaoyu
Medical Center Hospital of Qionglai City
Outcome results
None listed