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Effects of Ultrasound-Guided Bilateral Transversus Abdominis Plane Block Combined with Postural Management on Hypoxemia During Post-Anesthesia Recovery in Elderly Patients Undergoing Laparoscopic Surgery: A Prospective Multicenter 2×2 Factorial Randomized Controlled Trial

Effects of Ultrasound-Guided Bilateral Transversus Abdominis Plane Block Combined with Postural Management on Hypoxemia During Post-Anesthesia Recovery in Elderly Patients Undergoing Laparoscopic Surgery: A Prospective Multicenter 2×2 Factorial Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127334
Enrollment
Unknown
Registered
2026-06-29
Start date
2026-07-05
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxemia during anesthesia recovery in elderly patients undergoing laparoscopic surgery

Interventions

TAP Block Group:Ultrasound-guided bilateral TAP block
TAP plus Posture Group:Ultrasound-guided bilateral TAP block combined with head-up positioning
Control Group:Standard perioperative management
Head-up Position Group:30° head-up positioning

Sponsors

Fengxian People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Age >=65 years; 2. American Society of Anesthesiologists (ASA) physical status I–III; 3. Undergoing laparoscopic abdominal surgery under general anesthesia; 4. Able to understand the study and sign the written informed consent form.

Exclusion criteria

Exclusion criteria: 1. BMI >30; 2. Patients requiring emergency surgery; 3. Previous or current pulmonary disease, such as chronic obstructive pulmonary disease or asthma; 4. Previous pulmonary surgery or history of pneumothorax, pulmonary tuberculosis, or pleural effusion; 5. Anticipated difficult intubation; 6. Respiratory failure; 7. Severe cardiac disease, such as sinus node dysfunction, cardiac conduction block, or congestive heart failure; 8. Pregnancy; 9. Refusal to participate in this study.

Design outcomes

Primary

MeasureTime frame
Incidence of Hypoxemia During PACU Stay;Incidence of Severe Hypoxemia During PACU Stay;

Secondary

MeasureTime frame
Length of PACU Stay;PSQI Score on Postoperative Day 1;Incidence of Airway Intervention During PACU Stay;Resting VAS Pain Score at PACU Discharge;Resting VAS Pain Score on Postoperative Day 2;Incidence of Postoperative Rescue Analgesia;QoR-15 Score on Postoperative Day 1;Resting VAS Pain Score on Postoperative Day 1;Extubation Time;

Countries

China

Contacts

Public ContactQi Kong

Fengxian People's Hospital

15195477778@163.com+86 516 8112 7137

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026