Cardiopulmonary Dysfunction Related to Sarcopenia
Conditions
Interventions
Sponsors
People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for participants in the pre-sarcopenia and sarcopenia groups (1)Participants who meet the diagnostic criteria according to the 2025 consensus update of the Asian Working Group for Sarcopenia; (2)Participants aged 50-80 years; (3)Participants who agree to participate in this study and provide written informed consent. 2.Inclusion criteria for participants in the non-sarcopenia group (1)Participants aged >=65 and 28 kg for males or >18 kg for females; participants aged >=50 and 34 kg for males or >20 kg for females; (2)Participants aged 50-80 years; (3)Participants who agree to participate in this study and provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiac diseases, such as acute coronary syndrome within the past 6 months, implantation of a cardiac pacemaker, cardiac stent, or other metallic implants, or structural heart disease; 2. Patients with uncontrolled severe hypertension, such as systolic blood pressure >180 mmHg; 3. Patients with severe pulmonary diseases, such as severe chronic obstructive pulmonary disease, namely GOLD grade 3-4, interstitial lung disease, severe pulmonary infection, infectious pulmonary disease, asthma, or bronchiectasis; 4. Patients with severe brain diseases, such as cerebral hemorrhage or cerebral infarction; 5. Patients with severe liver diseases, such as liver cirrhosis or liver abscess; 6. Patients with severe kidney diseases, such as stage 5 chronic kidney disease or lupus nephritis; 7. Patients with a history of advanced malignant tumors; 8. Patients with hypoglycemia or acute diabetic complications; 9. Patients with severe hematological diseases; 10. Patients who have used glucocorticoids for a long time or at high doses; 11. Patients who have taken antibiotics or probiotics within the past 1 month; 12. Patients who have undergone major surgery recently, such as within the past 3 months; 13. Patients who have not provided informed consent, are unwilling to provide medical history information, or have incomplete data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function test;Echocardiography;Electrocardiogram;N-terminal pro-B-type natriuretic peptide;Functional exercise capacity assessment;Arterial stiffness assessment;Chest digital radiography;Muscle strength;Muscle mass;Traditional Chinese medicine syndrome elements;Diaphragm ultrasound assessment;Limb skeletal muscle ultrasound assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory test indicators; | — |
Countries
China
Contacts
Public ContactHe Weidong
People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine
Outcome results
None listed