CIN1?CIN2
Conditions
Interventions
Observation group:None
Sponsors
Guangdong Province Hospital for Women and Children Healthcare
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1.Patients with persistent HR-HPV infection for more than 1 year and pathological diagnosis of CIN 1 in cervical biopsy before treatment; 2.CIN 2 patients aged 20-35 years old who want to have children, the cervical transformation zone and the upper edge of the lesion are completely visible under colposcopy, and there is no HSIL, invasive cancer or glandular epithelial lesions in the cervical canal. 3.Have complete follow-up data;
Exclusion criteria
Exclusion criteria: 1. Patients whose pathological diagnosis is suspected or confirmed to be CIN 3 or higher, carcinoma in situ of the cervix, or invasive cervical cancer; 2. Patients with cytology results showing atypical glandular cells (AGC), atypical glandular cells favoring neoplasia (AGC-FN), cervical adenocarcinoma in situ (AIS), adenocarcinoma (AC), or suspected malignancy; 3. Patients with other reproductive tract malignancies; 4. Patients who are pregnant or breastfeeding; 5. Patients with immune system diseases, HIV infection, or who have been on long-term immunosuppressants in the past 3 months; 6. Patients with severe systemic diseases like heart, liver, or kidney failure who cannot tolerate treatment; 7. Patients with uncontrolled acute reproductive tract infections at the time of treatment; 8. Patients known to be allergic to the photosensitizer or its analogs, or who have porphyria, photosensitive disorders, or sunlight-related dermatitis; 9. Patients lost to follow-up or with incomplete clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Remission of lesions;High-risk HPV remission status; | — |
Countries
China
Contacts
Public ContactLi Zhimin
Guangdong Province Hospital for Women and Children Healthcare
Outcome results
None listed