Postoperative Pulmonary Complications (PPCs)
Conditions
Interventions
Conventional Tidal Volume Group:The tidal volume is set at 7 milliliters per kilogram of predicted body weight
Individualized Tidal Volume Group:The tidal volume is initially set at 7 ml/kg of predicted body weight, and then adjusted within the range of 4 to 10 ml/kg of predicted body weight to achieve a drivi
Sponsors
Huai'an First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Adult obese patients aged 18 to 75 years, with a body mass index BMI>=30 kg/m^2, and a moderate-to-high risk of postoperative pulmonary complications (as assessed by the ARISCAT score). 2.?Scheduled to undergo elective laparoscopic bariatric surgery. 3.?Signed informed consent obtained.
Exclusion criteria
Exclusion criteria: 1.?Patients with severe cardiovascular disease or severe hepatic or renal dysfunction. 2.?A history of severe complications, including pulmonary infection, pleural effusion, atelectasis, respiratory failure, or cardiogenic pulmonary edema. 3.?Contraindications to positive end-expiratory pressure (PEEP), such as tension pneumothorax, pulmonary bullae, severe barotrauma, hypovolemic shock, bronchopleural fistula, or increased intracranial pressure. 4.?Massive intraoperative hemorrhage (greater than 500 mL). 5.?Hemodynamic instability. 6.?A history of any form of prior lung surgery. 7.?Craniocerebral trauma, neuromuscular decline, or other diseases that impair respiratory function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PaO2/FiO2 ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory Mechanics Parameters;Postoperative Pulmonary Complications (PPCs); | — |
Countries
China
Contacts
Public ContactZhen Su
Huai'an First People's Hospital
Outcome results
None listed