Postoperative pain after uniportal thoracoscopic surgery
Conditions
Interventions
Control group:Ultrasound-guided paravertebral nerve block at T3–T7 levels was performed with 20 mL of liposomal bupivacaine (266 mg in total).
Experimental group A:Under direct thoracoscopic vision, three-point intercostal nerve block with liposomal bupivacaine (266mg/20 mL per vial) was performed at the 3rd, 4th, and 5th intercostal spaces
Experimental group B:On the basis of experimental group A, ultrasound-guided paravertebral nerve block at the T3–T7 level was added, using 20 mL of liposomal bupivacaine, 133 mg in total. A total of 2
Sponsors
Zhejiang Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18–75 years; 2. Scheduled to undergo unilateral lobectomy, segmentectomy or wedge resection via uniportal video-assisted thoracoscopic surgery (VATS); 3. ASA physical status classification Grade ?–?; 4. Signed informed consent preoperatively.
Exclusion criteria
Exclusion criteria: 1. Severe cardiopulmonary dysfunction (e.g., FEV1 < 40% of predicted value, NYHA class III–IV); 2. History of previous thoracic surgery resulting in abnormal anatomical structures; 3. Known hypersensitivity to bupivacaine or components of the liposomal formulation; 4. Presence of coagulation disorders or use of anticoagulants (anticoagulants must be discontinued until within a safe range); 5. Contraindications to paravertebral puncture (e.g., infection, spinal deformity, neurological diseases, etc.); 6. Inability to cooperate with pain assessment or communication disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dynamic and static pain scores at 24 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical Procedure & Operative Time;Dynamic and static pain scores at 12 and 48 hours postoperatively.;Time to discharge;Extubation time;Postoperative complications;Opioid consumption (fentanyl equivalents);Location and Character of Pain; | — |
Countries
China
Contacts
Public ContactJian Zeng
Zhejiang Cancer Hospital
Outcome results
None listed