None
Conditions
Interventions
Underweight group (BMI=28.0):None
Sponsors
Beijing Sport University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18-60 years. 2.Voluntary participation with written informed consent. 3.Able to complete questionnaires, anthropometric and DEXA measurements, and a single fasting venous blood draw. 4.Classifiable as underweight, normal weight, overweight or obese.
Exclusion criteria
Exclusion criteria: 1.Athlete grade or professional sports training background. 2.Severe cardiovascular/cerebrovascular, metabolic (including diabetes), hepatic/renal, endocrine, infectious, autoimmune or digestive diseases. 3.Regular use of hormones, glucose-lowering, lipid-lowering or antibiotic drugs within the past 3 months. 4.Acute infection, fever, trauma or surgery within the past 2 weeks. 5.Vigorous exercise within 48 hours, or heavy alcohol intake within 24 hours, before sampling. 6.Long-term smoking or long-term excessive alcohol consumption. 7.Pregnant or lactating women. 8.Blood donation within the past month, or concurrent participation in other interventional human studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| N-acetyl amino acid profile;N-Acetylvaline (NAV) concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body composition(BMI, waist-hip ratio, body fat %, lean mass);Fasting glucose, insulin, HbA1c, lipid panel;Exercise/energy metabolism-related metabolites (lactate, pyruvate, BCAAs, amino acids, Lac-Phe);Untargeted metabolomics;Physical activity level;Basic physiological indicators (such as resting blood pressure, heart rate, grip strength, etc.); | — |
Countries
China
Contacts
Public ContactLijun Shi
Beijing Sport University
Outcome results
None listed