Primary Diseases: Hypertension, Pan-vascular Diseases, Hypertensive Target Organ Damage. Related Adverse Events and Comorbidities: Myocardial infarction, Stroke, Heart failure, Coronary artery ischemic lesions, Peripheral arterial disease, Carotid/renal artery stenosis, Aortic diseases, End-stage renal disease, Cardiac death, Arrhythmia, Cardiogenic shock, Cardiometabolic abnormalities, Sleep and
Conditions
Interventions
Luohe Hypertension and Panvascular Disease Cohort Study:None
Sponsors
Luohe Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 years or older. 2.Receiving hospitalization, consultation, follow-up or management at Luohe Central Hospital or its affiliated network hospitals, with complete access to major clinical and key diagnostic data. 3.Meeting the diagnostic criteria for hypertension. 4.Having at least one pan-vascular assessment record at baseline, such as baPWV/ABI, carotid ultrasound, renal artery imaging, cranial imaging, electrocardiogram, echocardiogram or other vascular/target organ examinations. Completion of baPWV/ABI is recommended; reasons for failure will be documented, which shall not be a sole exclusion factor. 5.The participant, legal representative or regular caregiver is willing and able to complete 30-year annual follow-up via telephone, outpatient visit or medical records, and provides valid contact information for themselves and at least one relative.
Exclusion criteria
Exclusion criteria: 1.Critically unstable acute conditions judged by the research team to preclude baseline assessment or follow-up. 2.Acute unstable phase of myocardial infarction, acute coronary syndrome, acute stroke or acute decompensated heart failure. 3.Active malignancy, end-stage organ failure or other severe non-cardiovascular diseases with limited life expectancy (< 1 year) or inability to complete follow-up. 4.Severe mental disorders, disturbance of consciousness or cognitive impairment unable to cooperate with questionnaires and follow-up, with no eligible legal representative or caregiver available. 5.No valid contact information or confirmed inability to receive long-term follow-up. 6.Pregnant women (confirmed or clinically suspected pregnancy). 7.Severe missing key clinical or pan-vascular assessment data that prevents baseline risk evaluation and long-term outcome judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| First MACCE occurring after baseline. MACCE consists of all-cause death (cardiac death will be identified and documented), non-fatal myocardial infarction, non-fatal stroke, hospitalization for heart; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac death.; | — |
Countries
China
Contacts
Public ContactWang Haoran
Luohe Central Hospital
Outcome results
None listed