The incidence of ipsilateral shoulder pain (ISP) after thoracoscopic surgery ranges from 21% to 97%, which has become a major clinical issue affecting patients' rehabilitation quality. ISP is defined as ipsilateral shoulder and back pain occurring on the thoracic surgical side within one hour postoperatively.
Conditions
Interventions
Perineural group:Normal saline 5 mL via intravenous injection
thoracic paravertebral block with 20 mL mixture of 0.5% ropivacaine plus dexamethasone 4 mg
Intravenous group:Normal saline 4 mL + dexamethasone 4 mg(plus 5ml) via intravenous injection
thoracic paravertebral block with 0.5% ropivacaine 20 mL.
Control group:Normal saline 5 mL via intravenous injection
Sponsors
Zigong First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18–75 years; 2. BMI 18.5–28 kg/m^2; 3. ASA physical status I–III; 4. Undergoing an elective unilateral thoracoscopic lobectomy; 5. Estimated operative time 1–3 hours; 6. Written informed consent obtained.
Exclusion criteria
Exclusion criteria: 1.Contraindications of thoracic paravertebral block; 2.Allergy to local anesthetics or dexamethasone; 3.Long-term glucocorticoid use; 4.History of chronic pain; 5.Severe hepatic or renal impairment; 6.Psychiatric disorders or cognitive impairment; 7.Use of NSAIDs or opioids within 24 hours before surgery;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative ipsilateral shoulder and back pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of the surgery;Complication indicators;Blood glucose;Inflammatory factors (C-reactive protein);Sleep quality assessment;Long-term evaluation;Perioperative anesthetic dosage;Postoperative analgesic consumption; | — |
Countries
China
Contacts
Public ContactQian Liu
Zigong First People's Hospital
Outcome results
None listed