Pulmonary hypertension (PH) and its subtypes: 1. Pulmonary arterial hypertension (PAH)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age and Consent: Aged 18 to 80 years, capable of providing written informed consent voluntarily. 2. Diagnosis: Confirmed diagnosis of PH by RHC (mPAP >20 mmHg and PVR >2 Wood units at rest). 3. Classification: Completed comprehensive PH classification evaluation (including echocardiography, pulmonary function tests, V/Q scan or CTPA).
Exclusion criteria
Exclusion criteria: 1. Health Status: Diagnosis of advanced malignant tumors or end-stage conditions leading to an estimated life expectancy of less than 1 year. 2. Vulnerable Populations: Pregnant or lactating women. 3. Compliance/Cognitive Impairment: Poor adherence or inability to comply with follow-up; Presence of mental, intellectual, or language disorders hindering cooperation. 4. Investigator's Discretion: Any other condition deemed unsuitable by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in Pulmonary Hypertension Risk Stratification;Interval Between Pulmonary Hypertension-Related Hospitalizations;Change in six-minute walk distance (6MWD);Reduction in NT-proBNP;Improvement rate in WHO functional class;Clinical worsening events; | — |
Countries
China
Contacts
The Affiliated Hospital of Xuzhou Medical University