Sarcopenia in older adults, Voice Disorders
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Older adults (60 years old or above, according to the World Health Organization); 2. Formal diagnosis of sarcopenia according to the Asian Working Group for Sarcopenia (AWGS) 2019 Consensus Update on Sarcopenia Diagnosis and Treatment; 3. Cognitive function capable of conducting vocal assessment and voice therapy; 4. Informed consent to voluntarily participate in research.
Exclusion criteria
Exclusion criteria: 1. Centenarians (aged at or above 100); 2. Absolute bed rest (of 5 days or more) in the past 6 months, according to the European Working Group on Sarcopenia in Older People 2(EWGSOP2)2019 revised European consensus on definition and diagnosis; 3. Confirmed ENT diagnosis of laryngopharyngeal reflux (LPR); 4. History of laryngeal or head and neck diseases or surgery; 5. History of vocal training; 6. History of voice therapy; 7. History of severe heart, brain, lung, liver, kidney, or neurological diseases, malignancy, cachexia; 8. Taking medications causing severe loss of appetite.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Laryngeal endoscopic assessment of normalized glottal gap area (NGGA);Voice quality assessment using CAPE-V (overall severity, roughness, breathiness, strain, pitch, loudness);Acoustic parameter (fundamental frequency);Acoustic parameter (intensity);Acoustic parameter (jitter);Acoustic parameter (shimmer);Acoustic parameter (harmonics-to-noise ratio);Acoustic parameter (smoothed cepstral peak prominence);Aerodynamic parameter (mean flow rate);Aerodynamic parameter (phonation threshold flow);Aerodynamic parameter (subglottal pressure);Aerodynamic parameter (phonation threshold pressure);Aerodynamic parameter (laryngeal airway resistance); | — |
Secondary
| Measure | Time frame |
|---|---|
| Voice-Related Quality of Life (V-RQOL);Vocal Fatigue Index (VFI);Aging Voice Index (AVI);Lung function parameter (vital capacity, VC);Lung function parameter (forced expiratory volume in one second, FEV1);Lung function parameter (forced vital capacity, FVC);Lung function parameter (FEV1/FVC);Lung function parameter (peak expiratory flow, PEF);Lung function parameter (maximum mid-expiratory flow, MMEF); | — |
Countries
China
Contacts
The Second Affiliated Hospital, Xiamen Medical College