Pelvic Lipomatosis
Conditions
Interventions
Doxazosin Mesylate treatment group:None
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years, regardless of gender. 2. Diagnosed with pelvic lipomatosis via imaging standards (ultrasound, CT, MRI). 3. International Prostate Symptom Score (IPSS) >= 8 points (this score is only applicable to male patients). 4. Diagnosed with hydronephrosis based on imaging examinations (ultrasound, CT, MRI) and clinical evidence, while meeting the diagnostic criteria for hypertension. Note: Male patients must meet either criteria 1, 2, 3 or 1, 2, 4simultaneously. Female patients must meet criteria 1, 2, and 4 simultaneously.
Exclusion criteria
Exclusion criteria: 1. Hypotension; 2. Urinary tract infection, urinary calculi and tumor; 3. A history of transurethral surgical procedures; 4. Patients with complicated neurological diseases, severe constipation and dyspepsia; 5. Patients who have used alpha-1 adrenergic blockers or M-cholinergic blockers within 1 month; 6. Patients who cannot tolerate the adverse reactions of doxazosin mesylate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lower urinary tract function (IPSS score, OABSS score, urine flow rate improved/no significant change compared to before medication);Blood pressure changes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Medical Outcomes Study 36-Item Short Form Health Survey Score;Patient Assessment of Constipation-Symptoms Score;Hospital Anxiety and Depression Scale Score; | — |
Countries
China
Contacts
Public ContactXuesong Li
Peking University First Hospital
Outcome results
None listed