Uterine Prolapse (UP)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Women aged >= 18 years; 2.Clinically diagnosed or suspected POP, POP-Q stage >= I; 3.Able to complete clinical POP-Q assessment cooperatively; 4.Able to tolerate transrectal biplane ultrasonography; 5.Able to perform effective Valsalva maneuver; 6.With complete clinical data available; 7.Fully understood the study and voluntarily provided written informed consent; 8.Participants enrolled in the cervical length accuracy verification cohort are scheduled to undergo hysterectomy or trachelectomy, with surgical and pathological reference measurements available;
Exclusion criteria
Exclusion criteria: 1.Patients with prior total hysterectomy and unavailable cervical-related indicators; 2.Patients with pelvic malignant tumors or suspected malignancy; 3.Patients with severe genital tract malformations interfering with localization of cervical or vaginal structures; 4.Patients who underwent pelvic floor reconstruction within the past 6 months; 5.Patients with acute infection of the vagina, cervix, pelvis or rectum; 6.Patients with severe anorectal diseases who cannot undergo transrectal examination; 7.Prior history of pelvic radiotherapy; 8.Unable to perform effective Valsalva maneuver; 9.Image quality inadequate for identification of key structures; 10.Pregnant females or those within 6 months postpartum; 11.Participants with BMI >= 35 kg/m^2 will not be directly excluded, but will be separately labeled for subgroup and sensitivity analyses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Curvilinear cervical length; | — |
Secondary
| Measure | Time frame |
|---|---|
| Straight-line cervical length;POP-Q landmarks; | — |
Countries
China
Contacts
Peking University Shenzhen Hospital