Pulmonary nodule(s)
Conditions
Interventions
Ropivacaine group (RO group):Analgesic Effect of Ultrasound-Guided Retrolaminar Block with Ropivacaine in Patients Undergoing Video-Assisted Thoracoscopic Lung Resection
Liposomal bupivacaine group (LB group):Analgesic Effect of Ultrasound-Guided Retrolaminar Block with liposomal bupivacaine in Patients Undergoing Video-Assisted Thoracoscopic Lung Resection
Sponsors
Jiangsu Province Geriatric Hospital(Geriatric Hospital of Naning Medical University, Jiangsu Province Official Hospital, Jiangsu Province Geriatric Hospital Telehealth Services)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age 18–75 years; 2.BMI 19–30 kg/m^2; 3.ASA physical status II or III; 4.Scheduled to undergo elective VATS pulmonary resection under general anesthesia; 5.Able to understand the pain scoring method and comply with follow-up assessments before surgery; 6.Willing to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1.New York Heart Association (NYHA) functional class III or IV; 2.Cardiac conduction block; 3.Unstable coronary artery disease; 4.Insulin-dependent diabetes mellitus; 5.Renal or hepatic dysfunction; 6.Coagulation disorders or use of oral anticoagulants; 7.Alcohol abuse or opioid dependence; 8.Uncontrolled psychiatric disorders (e.g., anxiety, depression, schizophrenia); 9.Pregnancy or planned pregnancy; 10.Significant alteration of local anatomical structures; 11.Or known allergy to local anesthetics or study medications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative NRS pain scores at rest and during movement within 0–72 hours postoperatively (expressed as the area under the curve, AUC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Activities of daily living at 72 h postoperatively;Time to first initiation of PCIA;postoperative NRS scores at rest and during movement from 0–72 h;total postoperative intravenous opioid and non-opioid consumption within 72 hours after surgery;NRS pain scores during movement at postoperative day 14 and 3 months;QoR-15 score at 72 h postoperatively;Time to first ambulation and chest tube removal postoperatively; | — |
Countries
China
Contacts
Public ContactSiyang Xu
Jiangsu Province Geriatric Hospital(Geriatric Hospital of Naning Medical University, Jiangsu Province Official Hospital, Jiangsu Province Geriatric Hospital Telehealth Services)
Outcome results
None listed