Adjacent multilevel thoracolumbar osteoporotic vertebral compression fracture
Conditions
Interventions
Group 1:Bilateral percutaneous kyphoplasty
Group 2:Sequential Unilateral percutaneous kyphoplasty
Group 3:Cross Unilateral percutaneous kyphoplasty
Sponsors
Rui'an People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Aged >= 60 years; 2.Definitive diagnosis of adjacent >= 2-level thoracolumbar osteoporotic vertebral compression fractures (OVCFs) confirmed by X-ray, CT, and MRI; 3.Significant pain related to fractures, VAS score > 3 points; 4.Bone mineral density examination indicating osteoporosis (T-score = 12 months with the ability to complete follow-up; 8.Significant fracture-related pain with a VAS score > 3.
Exclusion criteria
Exclusion criteria: 1.Vertebral fractures caused by tumors, infection, tuberculosis, or other non-osteoporotic etiologies; 2.Presence of significant neurological deficits requiring decompression or internal fixation surgery; 3.Severe cardiac, pulmonary, hepatic, or renal insufficiency rendering the patient unable to tolerate surgery; 4.Coagulation disorders or long-term anticoagulant therapy that cannot be safely discontinued; 5.Moderate to severe psychiatric disorders or significant cognitive impairment precluding understanding of the study; 6.Previous surgical treatment involving the target vertebrae; 7.Any other conditions deemed inappropriate for enrollment by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ODI score;Operation time;number of cases with bone cement leakage;SF36 score;intraoperative blood loss;Intraoperative?fluoroscopy;Patients’ anesthesia satisfaction scores;number of perioperative cardiovascular and cerebrovascular adverse events;Investigators’ satisfaction scores;VAS score;Adjacent segment fracture; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital day;anterior vertebral body compression ratio of the fractured vertebra;Cement volume;Cobb angle;Hospitalization costs;anesthesia re-administration intention rate; | — |
Countries
China
Contacts
Public ContactHe Shaoqi
Rui'an People's Hospital
Outcome results
None listed