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Study on analgesic effect of bupivacaine liposome local infiltration anesthesia after anterior cruciate ligament reconstruction

Study on analgesic effect of bupivacaine liposome local infiltration anesthesia after anterior cruciate ligament reconstruction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127196
Enrollment
Unknown
Registered
2026-06-26
Start date
2025-09-25
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior cruciate ligament injury of knee joint, pain and instability of knee joint of affected limb

Interventions

No local anesthesia group:None
Cocktail group:None

Sponsors

Shandong Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Male or female, aged 18 or older. 2. Diagnosed with ACL injury in the knee and planned to undergo arthroscopic unilateral knee ACLR surgery; 3. Classified as ASA I-III, with a certain level of education, good understanding of Chinese language and writing, able to communicate with medical staff without barriers, can understand the Visual Analog Scale (VAS) for pain well, and can actively cooperate with related examinations; 4. The patient voluntarily participates in this trial, has signed the informed consent form, and will cooperate to complete all study assessments.

Exclusion criteria

Exclusion criteria: 1. Allergic or intolerant to local anesthetics; 2. Have recently used anesthetic or pain relief medication for more than three weeks; 3. Have nerve or muscle disorders in the limb being operated on; patients with other conditions that might affect postoperative recovery; 4. Patients who, in the past six months, have been treated for coronary artery issues, stent placement, deep vein thrombosis, pulmonary embolism, heart attack, or ischemic stroke; 5. Have severe liver or kidney problems, coagulation disorders, arrhythmias, infections, or other surgical contraindications; 6. Patients with any neurological or mental disorders that could affect postoperative pain or interfere with study assessments; 7. History of abusing opioids, other prescription medications, illegal drugs, or alcohol misuse, abuse, or dependence.

Design outcomes

Primary

MeasureTime frame
Visual analogue scale (VAS) was used to compare the average VAS scores at rest at 24, 48 and 72 hours after surgery between the two groups;

Secondary

MeasureTime frame
Scoring table such as qor-15;Postoperative knee function such as flexion angle;Using the Visual Analogue Scale (VAS) scores, we compared the VAS scores during both active and resting periods at each postoperative time point (6, 24, 48, and 72 hours) in the two groups of patients;Using Visual Analogue Scale (VAS) scores, we compared the average VAS scores during the activity periods at 6, 24, 48, and 72 hours after surgery between the two groups of patients;The patient's sleep condition three days after surgery;

Countries

China

Contacts

Public ContactLi Yi

Shandong Provincial Hospital

liyivincent@126.com+86 531 68776351

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 3, 2026