Temporomandibular joint and its surrounding structures skull base tumors
Conditions
Interventions
Experimental Group:Temporomandibular joint reconstruction with artificial prosthesis
Control Group:Autogenous BONE RECONSTRUCTION
Sponsors
Ninth People's Hosipital, Shanghai Jiao Tong University, School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old, regardless of gender; 2. The patient was diagnosed as a temporomandibular joint mass or a temporomandibular joint ear mass or a temporomandibular joint skull base mass or a temporomandibular joint skull base ear mass.
Exclusion criteria
Exclusion criteria: 1. Patients allergic to titanium implants; 2. Patients with acute or severe infection or acute exacerbation of chronic infection; 3. Patients with extensive soft tissue defects caused by surgery, and the postoperative wound was not covered by enough soft tissue; 4. Patients with radiation osteomyelitis, acute and chronic osteomyelitis, osteoporosis; 5. Patients with uncontrolled primary diseases of important organs such as heart, lung, brain and kidney; 6. People with mental illness; 7. Pregnant and lactating women; 8. Patients who are unable to cooperate with treatment; 9. Patients with advanced malignant tumors, distant metastasis and tumor recurrence; 10. Patients with advanced malignant tumors, distant metastasis and tumor recurrence; 11. Use of antibiotics or chronic anti-inflammatory therapy (=3 times per week) within 4 weeks before surgery; 12. Alcohol or chronic drug abuse; 13. Patients with severe immunodeficiency; 14. Uncontrolled masticatory muscle hyperfunction (night bruxism, clenching) leading to overload and loosening of titanium nails; 15. Patients who could not participate in the trial because of poor compliance according to the investigator; 16. Patients were enrolled in a clinical trial of another drug or device within the three months before surgery (study day 0).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum mouth opening; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality Of Life score;The recurrence rate;Pain;Diet;Mandibular function;Bone integration;Maxillofacial morphology;Lateral/forward movement; | — |
Countries
China
Contacts
Public ContactYang Chi
Ninth People's Hospital Affiliated to Shanghai JiaoTong University School of Medicine
Outcome results
None listed