Skip to content

Effects of 10 Hz rTMS, 1 Hz rTMS, iTBS, and cTBS on the Excitability of the Primary Motor Cortex (M1) Diaphragmatic Area and Pulmonary Function in Healthy Individuals

Effects of 10 Hz rTMS, 1 Hz rTMS, iTBS, and cTBS on the Excitability of the Primary Motor Cortex (M1) Diaphragmatic Area and Pulmonary Function in Healthy Individuals

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127155
Enrollment
Unknown
Registered
2026-06-25
Start date
2026-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Experimental group:On different test days, participants received four types of stimulation: 1Hz rTMS, 10Hz rTMS, iTBS, and cTBS, but only one type each time. All stimulations were applied to the M1 ha

Sponsors

The First Affiliated Hospital of Air Force Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 45, any gender. 2. In good health, with no history of serious heart, lung, neurological, or mental illnesses. 3. No TMS contraindications, such as intracranial metal implants, history of seizures, or serious head trauma. 4. Willing to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. People who have had rehabilitation treatment or surgery related to the diaphragm in the past month. 2. People who have participated in other clinical trials in the past month that could affect the study results. 3. People with communication problems, severe hearing or vision impairments, or cognitive dysfunction who can't complete the assessments. 4. People with a history of drug or alcohol abuse, or who have recently used drugs that could affect central nervous system excitability and TMS effects, including but not limited to benzodiazepine sedatives, anticonvulsants, antipsychotics, etc. 5. Women who are pregnant or breastfeeding.

Design outcomes

Primary

MeasureTime frame
Diaphragm motor evoked potential;

Secondary

MeasureTime frame
Resting pulmonary function parameters;

Countries

China

Contacts

Public ContactHua Yuan

The First Affiliated Hospital of Air Force Military Medical University

yuanhua@fmmu.edu.cn+86 29 8477 5439

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 3, 2026