Relapsed/refractory classical Hodgkin lymphoma
Conditions
Interventions
PR before BV-ICE
non-PR before BV-ICE:None
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.histopathologically and immunohistochemically confirmed classical Hodgkin lymphoma (cHL); 2.relapsed or refractory after first-line standard therapy; 3.age >=16 years; 4.expected survival >= 3 months; 5.adequate organ function;
Exclusion criteria
Exclusion criteria: 1.patients with other concomitant malignancies; 2.patients with severe cardiac, hepatic, renal, pulmonary, vascular, or endocrine diseases; 3.patients with known hypersensitivity to BV or any other drugs included in the regimen; 4.pregnant or lactating women; 5.patients deemed unsuitable for participation in this study by the investigators;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-Free Survival (PFS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease Control Rate (DCR);Adverse Events (AEs);Complete Response Rate (CRR);Event-Free Survival (EFS);Objective Response Rate (ORR);Duration of Response(DOR); | — |
Countries
China
Contacts
Public ContactMi Jianqing
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed