stroke
Conditions
Interventions
rTMS group:The rTMS group received rTMS treatment and sham rPMS stimulation.
rPMS group:The rPMS group received rPMS treatment and sham rTMS stimulation.
CPMS group:The CPMS group underwent rTMS and rPMS combined stimulation therapy.
Sponsors
Haikou People's Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Conforming to the diagnostic criteria in the "Diagnostic Points of Major Cerebrovascular Diseases in China 2019" and confirmed by head CT or MRI; 2. First stroke, or with a history of stroke but without residual neurological dysfunction, with a disease course of 2 weeks to 6 months; 3. Patient's vital signs are basically stable, with no recent progressive worsening of cerebrovascular disease, able to cooperate in completing rehabilitation training, and able to clearly express training sensations; 4. Affected lower extremity Brunnstrom stage II-IV, with lower extremity dysfunction (FMA-LE < 27 points); 5. Age 30 to 70 years; 6. Affected lower extremity modified Ashworth scale <= 2 grade; 7. Informed consent signed by the patient or their authorized representative.
Exclusion criteria
Exclusion criteria: 1. Presence of cardiac pacemaker, intracranial metal implant, history of coronary artery stent insertion, or other contraindications to rTMS; 2. Presence of lumbar metal implant or other contraindications to rPMS; 3. History of epileptic seizure or family history of epilepsy; 4. Comorbid severe primary diseases of the heart, lung, liver, kidney, or hematopoietic system; 5. Pregnant state.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Task State Oxyhemoglobin (HbO) Concentration;Root Mean Square (RMS);Integrated Electromyography (iEMG);Gait parameters of the affected lower limb: stride length, stride length, stride time, maximum hip flexion angle, maximum knee flexion angle, maximum ankle dorsiflexion angle.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl MeyerLower-Extremity Score;Postural Assessment Scale for Stroke Patients Score;Modified Barthel Index Score; | — |
Countries
China
Contacts
Public ContactShuyin Li/ Zhenhua Song
Haikou People's Hospital
Outcome results
None listed