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Study on the Prediction of Disease Progression in Femoral Head Osteonecrosis Using the Ratio of Signal Intensity between the Sclerotic Margin and Necrotic Area

Study on the Prediction of Disease Progression in Femoral Head Osteonecrosis Using the Ratio of Signal Intensity between the Sclerotic Margin and Necrotic Area

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127151
Enrollment
Unknown
Registered
2026-06-25
Start date
2026-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

avascular necrosis of femoral head

Interventions

Observation group:None

Sponsors

The Third Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Diagnosed with osteonecrosis of the femoral head (ONFH, ARCO I–III stages or JIC classification is clear); 2.With complete follow-up data and the final occurrence of collapse; 3.Before the collapse, there were regular imaging examinations (X-ray anteroposterior and frog position) within 0-12 months. 4.The image quality meets the requirements of the grayscale analysis. 5.The imaging can be clearly marked with the time interval between the image and the collapse.

Exclusion criteria

Exclusion criteria: 1.Having previously undergone surgical treatment for the femoral head (such as core decompression, osteotomy, etc.); 2.Poor imaging quality or inability to perform ROI measurement; 3.Combine severe bone and joint diseases (such as infections, tumors); 4.Incomplete follow-up information or unclear collapse time;

Design outcomes

Primary

MeasureTime frame
The occurrence of femoral head collapse in patients with femoral head necrosis within 4 months;

Countries

China

Contacts

Public ContactLi Ziqi

The Third Affiliated Hospital of Guangzhou University of Chinese Medicine

ionsev0214@126.com+86 20 22292983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 3, 2026