Lung cancer
Conditions
Interventions
observed group:Chemo-Immunotherapy combined with hyperfractionated radiotherapy
Sponsors
Tianjin Cancer Hospital Airport Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. On the day of signing the informed consent form, the age is >= 18 years old. 2. The World Health Organization physical condition score is 0 or 1 (on a 5-point scale; the higher the score, the more severe the disability). 3. The expected survival period is >= 12 weeks. 4. Lung cancer diagnosed by histological or cytological examination. 5. The pathological type is non-small cell carcinoma or small cell carcinoma. 6. The non-small cell carcinoma stage is based on the 8th edition of the International Association for the Study of Lung Cancer (IASLC) Thoracic Oncology.
Exclusion criteria
Exclusion criteria: 1. Had previously undergone surgery or radiotherapy; 2. There are uncontrolled concurrent diseases or persistent/active infections; 3. There is an active or previously existing autoimmune disease (within the past 2 years) or primary immunodeficiency disease; 4. There is a history of interstitial lung disease, non-infectious pneumonia or uncontrolled systemic diseases, including diabetes, hypertension, pulmonary fibrosis, acute lung disease; 5. Within the previous 28 days before the first administration, any major surgery requiring general anesthesia has been performed; there are underlying medical conditions that are unfavorable for the administration of the study drug, or may affect the interpretation of results, or may cause a high risk of treatment complications for the patient; 6. Participating in another therapeutic clinical study simultaneously; 7. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The occurrence time of radioactive lung fibrosis; | — |
Countries
China
Contacts
Public ContactWang Yuwen
Tianjin Cancer Hospital Airport Hospital
Outcome results
None listed