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The Research of prediction and mechanism of TACR1 rs3755468 single nucleotide polymorphism on postoperative nausea and vomiting mediated by SP

The Research of prediction and mechanism of TACR1 rs3755468 single nucleotide polymorphism on postoperative nausea and vomiting mediated by SP

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127149
Enrollment
Unknown
Registered
2026-06-25
Start date
2023-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative nausea and vomiting

Interventions

PONV group:None
Non PONV group:None

Sponsors

Stomatology Hospital,Zhejiang University School Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Han Chinese female patients undergoing oral surgery in the oral and maxillofacial surgery ward; 2.aged between 18 and 65 years old; 3.ASA grades I to II;

Exclusion criteria

Exclusion criteria: 1.Allergies to related drugs; 2.Smokers; 3.Pregnant and lactating patients; 4.Patients who cannot understand visual simulation scores; 5.Patients with a history of gastrointestinal ulcers; 6.Patients with liver and kidney dysfunction; 7.Neuropsychiatric patients; 8.Chronic pain patients; 9.Patients who have experienced nausea and vomiting or used antiemetic drugs within 24 hours before surgery;

Design outcomes

Primary

MeasureTime frame
Postoperative nausea and vomiting;TACR1 gene sequence;—

Countries

China

Contacts

Public ContactZhoupeng Zheng

Stomatology Hospital,Zhejiang University School Medicine

gemini753@qq.com+86 571 87213010

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 3, 2026