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Application of Blood Flow Restriction Combined with Low-Intensity Resistance Training in Peripheral Skeletal Muscle Activity Characteristics in Mechanically Ventilated Patients

Application and Demonstration of Blood Flow Restriction Combined with Low-Intensity Resistance Training in Peripheral Skeletal Muscle Activity Characteristics of Mechanically Ventilated Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127142
Enrollment
Unknown
Registered
2026-06-25
Start date
2025-05-18
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

critically ill patient

Interventions

control group:Implement active resistance training, including elastic band stretching training (upper limb resistance training), ankle dorsiflexion training (lower limb resistance training), and bridg
40% AOP group:Stretching training with elastic bands under 40% of upper limb AOP
Ankle dorsiflexion training under 40% lower limb AOP
Bridge motion in 40% of limb AOPs
60% AOP group:Stretching training with elastic bands under 60% of upper limb AOP
Ankle dorsiflexion training under 60% lower limb AOP
Bridge motion in 60% of limb AOPs
80%AOP group:Stretching training with elastic bands under 80% of upper limb AOP
Ankle dorsiflexion training under 80% lower limb AOP
Bridge motion in 80% of limb AOPs

Sponsors

Affiliated Hospital of Zunyi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age range: 18 to 65 years old;  2. ICU admission time>24 hours;  3. Stable vital signs, no use of vasoactive drugs or increase in vasoactive drug dosage within 2 hours;  4. Equipped with an arterial blood pressure monitoring device; 5. The skin of the thighs on both upper and lower limbs is intact and undamaged.

Exclusion criteria

Exclusion criteria: 1. Medical records and/or diagnosis of lower limb deep vein thrombosis and other vascular diseases by ultrasound doctors; 2. Due to lower limb fractures, history of fractures, or edema, it is not suitable for movement.

Design outcomes

Primary

MeasureTime frame
Cross sectional area and muscle thickness of biceps brachii;Cross sectional area and muscle thickness of radial wrist flexor muscle;Cross sectional area and muscle thickness of rectus femoris muscle;Cross sectional area and muscle thickness of the medial head of the gastrocnemius muscle;Incidence of ICU acquired frailty;

Secondary

MeasureTime frame
Mechanical ventilation time;ICU length of stay;Incidence of deep veins in lower limbs;

Countries

China

Contacts

Public ContactGu Tiantian

Affiliated Hospital of Zunyi Medical University

582184262@qq.com+86 182 7561 5846

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 3, 2026