Abdominal pain
Conditions
Interventions
Conservative treatment group:Conservative treatment (watchful waiting)
Laparoscopic cholecystectomy group:Laparoscopic cholecystectomy
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. At least 18 years old; 2. Eligible for early (laparoscopic)* cholecystectomy; 3. Full required diagnostic work-up of patient has been performed, including EUS; 4. First, second or third episode of IAP, in which at least one episode characterized by a negative EUS result has been reported; 5. Informed consent for participation was obtained;
Exclusion criteria
Exclusion criteria: 1. Patients with more than 3 episodes of idiopathic acute pancreatitis; 2. Diagnosis of chronic pancreatitis; 3. Diagnosis of necrotizing pancreatitis; 4. Current pancreatic malignancy or main-duct IPMN; 5. Prior cholecystectomy; 6. Documented etiology of acute pancreatitis; 7. Patients in whom complete diagnostic work-up including EUS is not possible (e.g. Roux-and-Y bypass); 8. History of pancreas divisum# #Imaging to rule out pancreas divisum not required; 9. Pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of acute pancreatitis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of biliary events;Severity of recurrent acute pancreatitis;Incidence of complications following laparoscopic cholecystectomy;Gallbladder pathology findings;Number of acute pancreatitis recurrences;Healthcare costs;Quality of life; | — |
Countries
China
Contacts
Public ContactEnqiang Mao
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed