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Effect of Multimodal Analgesia (MMA) Combined with Mindfulness-Based Stress Reduction (MBSR) on Analgesic Efficacy and Sleep Quality in Patients After Spinal Fusion Surgery: A Prospective Randomized Controlled Trial

Effect of Multimodal Analgesia (MMA) Combined with Mindfulness-Based Stress Reduction (MBSR) on Analgesic Efficacy and Sleep Quality in Patients After Spinal Fusion Surgery: A Prospective Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127116
Enrollment
Unknown
Registered
2026-06-24
Start date
2026-07-13
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scoliosis, lumbar disc herniation and spinal fracture

Interventions

Intervention group:Intensive multimodal analgesia (MMA) combined with mindfulness-based stress reduction (MBSR) therapy
Control group:Traditional postoperative analgesia protocol

Sponsors

Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients continuously selected at our center from February 2026 to August 2026, who plan to undergo spinal fusion surgery under general anesthesia, aged 18-70, with no gender restrictions.

Exclusion criteria

Exclusion criteria: 1. People who can't give informed consent before surgery or have trouble communicating; 2. Those with severe heart disease (NYHA class III or above), respiratory issues (oxygenation index 2 times the normal limit); 3. Anyone who is allergic or has contraindications to the pain medications or MBSR treatment used in this study; 4. Those with mental illnesses or a long history of taking psychiatric medications; 5. People with clotting disorders; 6. Those who can't cooperate with follow-ups or assessments; 7. Patients who refuse to join the study.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale (VAS);Pittsburgh Sleep Quality Index (PSQI);Anxiety and depression scores;

Countries

China

Contacts

Public ContactZhaochu Sun

Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)

suncc520@163.com+86 25 68303570

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 3, 2026